ADULTS WITH TYPE 2 DIABETES, ALONG WITH DIET AND EXERCISE

RETHINK THE MATH WHEN IT COMES TO A1c

GLYXAMBI can be used along with diet and exercise to improve blood sugar in adults with type 2 diabetes, and can be used in adults with type 2 diabetes who have known cardiovascular (CV) disease when empagliflozin (JARDIANCE), one of the medicines in GLYXAMBI, is needed to reduce the risk of cardiovascular death.

Early Intervention

Delayed intervention is associated with an increased risk of complications

Percent increase in CV events in patients with a 1-year delay in receiving intensive therapy and HbA1c ≥ 7% vs < 7% :* retrospective UK study (N=105,477)1

* Following adjustments for various confounding factors, p <0.01 for all HR, HbA1c, glycated haemoglobin; HF, heart failure; MI, myocardial infraction.

Reference

  • Paul SK et al. Cardiovasc Diabetol. 2015;14:100.

Early intensive intervention to achieve target HbA1c1

  • Same sequence of interventions but each staage of treatment is brought forward to provide better and more rapid glycaemic control
  • * HbA1c = hemohlobin A1c; OAD=oral antidiabetic drug.

Reference

  • Del. Prato S, Felton AM, Munro N, et al. Improving glucose management: ten steps to get more patients with type 2 diabetes to glycaemic goal. int j clin pract. 2005;59(11):1345-1355.