BackStepping on the brakes in kidney disease progression
18 May 2023
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- 00:00:16 CKD background video 00:02:36 Welcome remarks by Dr Allen Marlon Costales 00:06:53 Opening remark by Prof Paweena Susantitaphong (Chairperson) 00:15:21 Session 1: Improving renal outcomes in low albuminuria and low eGFR patients by Dr Brendon Neuen 00:26:32 Checkpoint: Evidence and practice interactive session 00:33:10 Session 2: EMPA-KIDNEY and SGLT2i across the full spectrum of kidney function and albuminuria by Dr Brendon Neuen 00:48:25 Case discussion by Assoc Prof Kajohnsak Noppakun 01:07:50 Q&A 01:08:19 In the patients with non-diabetic kidney disease, if the guideline comes up, what will be the recommendation for SGLT2 inhibitors usage in patients with non-diabetic kidney disease? 01:12:02 In a patient with end-stage renal disease with pain from chronic gouty arthritis and polyarthritis, what medications should we give? 01:14:08 Are SGLT2 inhibitors effective for heart failure? 01:16:01 What is the next step if the patient still has high levels of proteinuria after initiating an SGLT2 inhibitor and a full dose of RAS blocker? 01:22:18 Do you have experience with patients who have hyponatremia after receiving an SGLT2 inhibitor? 01:24:39 In a post-kidney transplantation setting, what is the role of SGLT2 inhibitors? 01:26:58 Would there be any safety considerations around using empagliflozin in patients with/developing cancer? 01:28:03 How would you manage a patient with high levels of proteinuria and low blood pressure? 01:29:05 Can we combine DPP4 with SGLT2 inhibitors in patients with persistent or high UACR? 01:30:02 Are SGLT2 inhibitors safe to use in elderly patients? 01:31:23 Do you have any specific analysis or post-hoc analysis for SGLT2 inhibitor use in the lower eGFR levels (< 20mL/min)? 01:32:48 Checkpoint: Evidence and practice interactive session 01:34:14 Key takeaways and closing
Date: March 2023. RIN No: SC-PH-04498
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Prof. Paweena Susantitaphong
Chulalongkorn University Bangkok Thailand
- Professor, Division of Nephrology, Department of Medicine, King Chulalongkorn Memorial Hospital
- Medical Degree at the Chulalongkorn University Bangkok Thailand
- Member International Society of Nephrology (ISN) and Regional Board Member ISN Oceana and SEA
- Fellow Royal College of Physicians of Thailand
- Adjunct Associate Professor, Tufts University School of Medicine, USA
- Secretary Fellowship Training Program, Hemodialysis Quality Committee Nephrology Society of Thailand
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Dr Brendon Neuen
George Institute for Global Health Australia
- Staff Specialist Nephrologist and Director of the Kidney Trials Unit at Royal North Shore Hospital
- Senior Research Fellow at the George Institute for Global Health, Australia
- Medical Degree at James Cook University with 1st Class Honours and an Academic Medal
- Masters in Global Health and Epidemiology from the University of Oxford under Clarendon Scholarship
- PhD, University of New South Wales with the Faculty Award for outstanding contribution to research
- Fellow of the Royal Australasian College of Physicians and a Fellow of the American Society of Nephrology
- Founding Secretariat of the SGLT2 Meta-Analysis Cardio-Renal Trialists' Consortium (SMART-C)
- He has published over 70 peer-reviewed articles in general medical and specialty journals (e.g. The Lancet, BMJ and Annals of Internal Medicine, Lancet Diabetes and Endocrinology, Circulation, and the Journal of the American Society of Nephrology)
- Serving on boards or committees of the Australasian Kidney Trials Network, Australian and New Zealand Society of Nephrology, and the International Society of Nephrology
- Editorial Fellow of the Journal of the American Society of Nephrology from 2019-2020
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Dr Kajohnsak Noppakun
Chiang Mai University Thailand
- Assistant Professor of Medicine: Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Thailand
- Medical Degree (First Honor), Residency Internal Medicine and Fellowship Nephrology at the Chiang Mai University Thailand
- Diploma in Clinical Tropical Medicine and traveler health Infectious Division (2006) and Research training in stem cell biology Stem cell institute (2009) University of Minnesota, USA
- Clinical research training Kidney/Pancreas transplant program (2010) Mayo clinic, Rochester Minnesota, USA
- Member Medical Association of Thailand, Royal College of Physicians Thailand, Nephrology Society of Thailand and the Thai Transplantation Society
- Subcommittee Member on Research, Thai Transplant Registry, Thai Renal Replacement Therapy Registry Nephrology Society of Thailand and Committee Member for National Licensing in transplant Medicine (kidney) Thai Transplantation Society
